Friday, February 21, 2025

Bad medicine.

"The domestic pharma industry may not be significantly impacted by potential US retaliatory tariffs as most exports to the US include low-cost, price-inelastic generics that remain in constant demand." "Indian pharma exports to the US, valued at $10 billion, mainly include oral formulations," as "India is a major supplier to the US, providing over 45% of its generic medicines, driven by an ageing population and demand for cost-effective healthcare.' TOI. Unfortunately, it's not all good news. "Generic drugs made in India are related to 54% more severe adverse events, including hospitalization, disability and death, compared to the equivalent generic drugs made in the US, a new study has found. The findings were largely driven by 'mature generic drugs' - or those that had been in the market for a long time." "About 93% of generic drugs from emerging economy countries are made in India." ET. Since these drugs have been accepted for a long time, it may have bred complacency, indifference or an attempt to reduce costs by cutting corners. "The Center for Drug Evaluation and Research (CDER), a division of US Food and Drug Administration (FDA), has expressed concern over the quality of drugs manufactured in India, asserting that it found violations at 11% of the facilities it inspected in the country, the highest in any other global region." BS. How shameful! It gets worse. Aveo Pharmaceuticals, based in Mumbai, "is manufacturing unlicensed, highly addictive opioids and exporting them illegally to West Africa where they are driving a major public health crisis in countries like Ghana, Nigeria, and Cote d'Ivoire, BBC Eye investigation has revealed." "On 5 October 2022, the World Health Organisation (WHO) announced that four cough medicines, made by the Haryana-based manufacturer, Maiden Pharma, were suspected to have caused the deaths of 66 children in the West African nation, The Gambia." They were found to contain the highly toxic poison diethylene glycol, wrote Priyanka Pulla. In 2021, injections of Remdesiver were found to cause high fever, rigors and a dramatic drop in blood oxygen levels in patients sick with Covid. "Only the Bihar regulator identified the cause." "Their testing found Cadilla's batch V100167to contain bacterial endotoxins" which can cause "life-threatening septic shock in humans," wrote Pulla. Medicines enter our bodies, as does food. And so, "In the three years leading up to March 2023, Indian authorities tested 43 million food samples. Turns out, one in four did not conform to domestic food safety laws. Of these, one in every six were either 'unsafe' or 'substandard'," wrote Sayantan Bera & Suneera Tandon. Indian companies are equal opportunity killers. Because they are never punished. Probably bribe their way out. And that has caused problems for one. "The US Securities and Exchange Commission has asked Indian authorities for help in its investigation of Adani Group founder Gautam Adani and his nephew over alleged securities fraud and a $265-million bribery scheme." BS. If India helps, Adani may have to go to the US where he may be arrested. If India refuses, the New York court could issue an international arrest warrant for him or even fine the Indian government. Very confusing.         

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